Product Information

Mitogen-activated protein kinase 7(ERK5) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported

Immunogen/Specificity:
Ni-NTA purified truncated recombinant human ERK5 expressed in E. Coli strain BL21 (DE3)

Applications :
Western Blot: Dilution 1: 2,00- 1: 1,000
IHC£¨P£©: Dilution 1: 100- 1: 500
IHC£¨F£©: Dilution 1: 200- 1: 500
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Formulation
Antibodies are purified by protein G affinity chromatography.

Size: 0.1mg

Reference:
1. Knaus, U.G. Regulation. Science 1992. 224: 1312-1315.

Species: Human

Storage and Stability: stored at -20 C
 

Be the first to review this product!

Price: $425.00

• Tell a Friend
• Write review / comment